Pharmacologic modulation of splanchnic blood flow

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Splanchnic ischemia may be involved in the development of multiple organ failure. Vasoactive agents may influence not only splanchnic blood flow but also the distribution of blood flow within the gut and the balance between oxygen supply and demand in the splanchnic area. This article focuses on the effects of pharmacologic agents including adrenergic agents, prostacyclin, nitric oxide donors or inhibitors, and hemoglobin solutions on splanchnic blood flow.

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