Neurobiology of schizophrenia

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Abstract

There are widespread abnormalities of brain structure and function in schizophrenia, especially in multimodal association cortex of the frontal and temporal lobes. Evidence of dopaminergic disorder continues to accumulate, but other neurotransmitters are also implicated. Current evidence suggests that the wide-ranging neurobiological abnormalities reflect disturbed connectivity between brain regions arising from disordered neural development.

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