Depression after stroke

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Abstract

During the past year, significant contributions have been made to the literature on post-stroke depression. These studies have confirmed the importance of left-anterior cerebral hemisphere lesion in the production of major depression and identified this as a phenomenon which is most evident during the acute post-stroke period. In addition, premorbid and post-stroke risk factors such as cerebral atrophy, history of psychiatric disorders, negative life events, neuroticism, aphasia, living alone, and few social contacts, have been identified as increasing the risk of post-stroke depression. Finally, a new study has indicated that the risk of mortality, during a 10-year follow up, is increased 3.5 times by the existence of acute post-stroke depression.

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