Strategies for the diagnosis of metabolic syndrome

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The components of metabolic syndrome are insulin resistance, hyperinsulinism, central obesity, dyslipidemia, hypertension, and impaired glucose tolerance or non-insulin-dependent diabetes mellitus. There is extensive overlap of different abnormalities between each disorder of the metabolic syndrome. Consequently, diagnosis of the metabolic syndrome requires screening for each abnormality if one component has been verified. The crucial issue is that individual components per se are risk factors for coronary heart disease and consequently their clustering in the metabolic syndrome aggravates the risk of coronary heart disease.

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