Does Faecal Occult Blood Test (FOBT) screening lead to detection of earlier stage cancer and increased operative rates?: P123

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Aim:Faecal occult blood test (FOBT) based screeningprogrammes have been shown to reduce mortality from colorectal cancer. We aimed to see whether our screening detected cancers were of an earlier stage (Dukes A & B).Method:All patients between the ages of 60 & 69 years within our centre population were invited to participate in the BCSP between 1.10.2006 and 30.9.2009. Patients with positive tests were offered colonoscopy. Non-screened colorectal cancer patients detected over the same period and surgical management decisions were identified from the colorectal cancer database.Results:Screened population: 67 cancers, mean age 67.2 years, 19 female. Operative resection: 52 (78%), polypectomy: 7, non-operative: 8. Non-screened population: 428 cancers detected, 261 (68%) were treated surgically, mean age 69.9 years, 137 female. A greaterproportion of cancers were detected at an early stage in the screened cohort: 48/67 (71.6%) vs 174/290 (60%), (P = 0.077) and in male patients: screened 48/67 (71.6%) vs non-screened 153/290 (52.7%), (P = 0.005). There was no significant difference in theproportion of cancersproceeding to surgery, location of cancers or theproportion treated laparoscopically.Conclusion:Our FOBT based screeningprogramme for colorectal cancer has increased theproportion of patients detected with early stage disease, particularly in men.

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