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This study was performed to evaluate impact of intraoperative esophageal Doppler-guided intravenous fluid administration on complication rates and length of stay in elective major colorectal resections.Prospectively collected data on consecutive patients who underwent elective major bowel resections by a single surgeon at a single institution were extracted from an approved database. A nasoesophagealprobe was inserted after general anaesthesia induction and removed after surgery. Endpoints were major complication rates (defined as adverse events requiring re-intervention) and length of stay (defined as date of surgery until date of discharge). Values are medians (ranges).From 10/08-03/10, 100 (56 males, 44 females) patients aged 54 (19-93) years with BMI of 26.4 (16.8-49.6), POSSUM score of 16 (12-23), and overallpredicted mortality rate of 2% (1-17) underwent elective colorectal resection. Fifty-seven percent hadprevious abdominal surgery. Operative time was 120 (30-600) min; estimated blood loss was 50 (20-1500) ml. Intraoperative fluid administration was 3000 (100-7500) ml crystalloid and 500 (0-2500) ml colloid. Major complication rate was 5.0%, with no mortality. Length of stay was 6 (2-15) days.Intraoperative esophageal Doppler-guided intravenous fluid administration resulted in a 5% major complication rate and 6-day hospital stay for patients who underwent elective major colorectal resections.