Percutaneous Tibial Nerve Stimulation (PTNS) for slow transit constipation: a pilot study: LTP46

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Aim:Constipation is a chronic bowelproblem with debilitating effects on patients' quality of life. This study aimed to evaluate the effectiveness of PTNS in patients with slow transit constipation.Method:Twelve patients (11 women, median age 46.5 years [range 21-69]) with slow transit constipation participated in the study. Patients had 12 sessions (30 min per session) of PTNS with 1-3 sessions per week. Symptoms were evaluatedpre-and post-treatment using a standardised constipation score (score 0-31, 31 being worst) as theprimary outcome. Other outcome measures included colonic transit study, bowel diary and Patient Assessment of Constipation Quality of Life (PAC-QOL).Results:Constipation score improved significantly from a median of 19 (range 10-24) to a median of 14.5 (range 9-20) (P = 0.014). The PAC-QOL also showed significant improvement from a median of 2.605 (range 1.360-3.610) to a median of 1.430 (0.390-3.780) (P = 0.046). Bowel frequency increased, the usage of laxatives and the number of retained markers in the colonic transit study both decreased, although they were not statistically significant.Conclusion:PTNS has potential as an affordable and minimally invasive treatment for slow transit constipation. A randomised controlled study is needed to establish the efficacy.

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