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The study is apreliminary valuation of Starion efficacy in vessels sealing system of sutureless hemorrhoidectomy.Twenty patients with grade 4° hemorrhoids were treated by Starion hemorrhoidectomy and classic Milligan-Morgan operation into two randomized groups of 10 patients. All were operated under local and sacral block anaesthesia. The mean hospital stay was about 6 (±1) hours. The operative details, operating time, perioperative and postoperative pain scores, blood loss, early and delayed complications and return to normal activity were recorded. The follow-up was at 1, 2, 4 and 12 weeks after surgery.The mean operative time, blood loss, hospital stay, early and delayed complications weren't significantly different between the two techniques. Lower pain score (VAS 3-4 vs 6-7) and reduction of analgesic drugs waspresent (P < 0.001 in perioperative and P < 0.005 in postoperative time) in Starion group. One patient with anal stenosis requiring treatment was encountered by classic hemorrhoidectomy.Thepreliminary results of Starion hemorrhoidectomy are favourable. It seems a sure and effective operation forprolapsed hemorrhoids, comparable to classic Milligan-Morgan hemorrhoidectomy. Patients can be treated by ambulatory surgery better than classic intervention because derive a short-term benefit of less pain and less analgesic drugs.