Quality of life and fecal continence grade after total colectomy (TC) versus reconstructiveproctocolectomy (RPC) for familial polyposis: P119

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Aim:To compare quality of life and fecal continence grade of TC versus RPC in patients with familial polyposis (APC and MYH mutations).Method:SF-36 questionnaire and the Wexner continence score were sent to 51 polyposis patients who had been operated on from 1987 to 2009. Wexner score > 7 was considered poor continence grade. A matched control group (n = 1094) was used for comparison of SF-36 results.Results:Forty patients (16 female) with mean age (range) of 47 (26-77 years) answered the questionnaires with a mean ± SD follow-up of 100 ± 70 months. We performed 26 RPC (22 APC; 4 MYH) and 14 TC (7 APC; 7 MYH). The mean scores of SF-36 for physical component were 71 ± 23 in RPC and 60 ± 13 in TC (P = 0.07); for the mental component 72 ± 22 in RPC and 60±15 in TC (P < 0.05). No significant differences were found in the comparison of SF-36 results of the 40 patients study with the control group. The mean Wexner score were 4.4 ± 5.0 in RPC and 8.1 ± 4.4 in TC. This score was poor in 27% of RPC patients versus 64% of TC patients (P < 0.05).Conclusion:This study suggests that familial polyposis patients who had RPC had a better quality of life and continence grade than the TC group.

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