Use of the number of lymph nodes topredict oncolocical outcomes in colorectal cancer: P147


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Abstract

Aim:Lymph node (LN) examination is a measure of quality for colorectal cancer surgery. Expert groups recommend a minimum of 12 LN to achieve a high degree of accuracy. We have analyzed the number of LN (‡12 nodes) aspredictor of survival and recurrence in a cohort of patients with colorectal cancer.Method:We included all patients undergoing surgery for CRC between 2000 and 2005 in a referral center. Two groups were evaluated: group 1 (LN ‡12) and group 2 (< 12 LN). The survival and recurrence rate were analyzed by Kaplan-Meier curves.Results:Ninety-eight patients were included. Sixty three percent of patients had 12 or more lymph nodes analyzed. The average number of nodes in groups 1 and 2 were 19 ± 8.1 and 7 ± 2.7, respectively. Overall survival and recurrence rate were 89% and 27.5%, respectively. The 5 year survival rate in groups 1 and 2, were 96% vs 78% (P = 0.013), respectively. When analyzing survival by stage, differences were found on stage II patients at 3 and 5 years (P < 0.05).Conclusion:The number of lymph nodes is an independent survivalpredictor and can be used as a quality measure in colorectal cancer surgery.

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