Random and food-directed activity in hyperphagic and normal rats

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Using obese hypothalamic hyperphagic rats, recently operated nonobese hyperphagic rats, and normal control animals, random activity before, during, and after food deprivation, and food-directed activity during deprivation were measured. Random activity was greater in normal animals, and they showed greater increase during deprivation. Under low-work conditions hyperphagics showed more food-directed bar pressing, but they showed less under high-work conditions. It was concluded that hyperphagic animals show a lowered drive to obtain food and that nonobese hyperphagics are influenced more by food deprivation than are obese animals. (PsycINFO Database Record (c) 2006 APA, all rights reserved)

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