The anorexigenic action of dextro-amphetamine sulfate upon feeding responses of differing strength


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Abstract

“By feeding daily during a fixed 2-hr. interval over … five weeks, a strong eating response was established in a group of mature male albino rats. During this period, a matched group was fed the same diet ad libitum. Within a balanced latin square design, both groups were then injected intraperitoneally with varying dosages of dextro-amphetamine sulfate, 20 min. prior to the regularly scheduled feeding interval of the trained group. It was reasoned that because of the stronger eating response, the drug would exercise less anorexigenic effect on the immediately subsequent 2-hr. food intake of the trained group. Both groups [had lowered] … food intake with increasing dosage. In disagreement with prediction, the trained group was equally affected.” From Psyc Abstracts 36:01:1DK79S. (PsycINFO Database Record (c) 2006 APA, all rights reserved)

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