Cerebral cholinesterase activity and “hypothesis” behavior in a problemless maze

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“Twenty-eight rats were run in a Krech Hypothesis Apparatus from which all blocking doors were removed. Following behavioral testing, assays were made of cerebral cortical cholinesterase activity. A correlation of -.44 was found between cholinesterase activity and the tendency to prefer spatial, as against visual, orientation in the maze. This correlation is opposite in sign, and differs significantly, from the positive correlation previous experimenters (Krech et al.: 1956, 1954; Rosenzweig et al., 1958) found between these variables when, in the same maze, blocking doors were present and the maze was unsolvable …. [The important finding of this experiment] is that normally occurring differences in cortical cholinesterase activity are related to behavioral differences.” From Psyc Abstracts 36:01:1DJ68P. (PsycINFO Database Record (c) 2006 APA, all rights reserved)

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