Effect of pentobarbital sodium on the behavior of rats in the Krech Hypothesis Apparatus


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Abstract

“Twelve male rats were trained to go to the left in the Krech Hypothesis Apparatus. The animals were then divided into two groups, and the maze was made unsolvable. Group I then received saline injections, and Group II received injections of pentobarbital sodium. The results show a significant tendency for the left-going behavior to persist under pentobarbital sodium in Group II, but not with saline injections in Group I. These results were interpreted as further evidence for a correlation between the level of acetylcholine metabolism and the capacity for more adaptive behavior.” From Psyc Abstracts 36:01:1DK72M. (PsycINFO Database Record (c) 2006 APA, all rights reserved)

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