Effect of pentobarbital sodium on the behavior of rats in the Krech Hypothesis Apparatus

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“Twelve male rats were trained to go to the left in the Krech Hypothesis Apparatus. The animals were then divided into two groups, and the maze was made unsolvable. Group I then received saline injections, and Group II received injections of pentobarbital sodium. The results show a significant tendency for the left-going behavior to persist under pentobarbital sodium in Group II, but not with saline injections in Group I. These results were interpreted as further evidence for a correlation between the level of acetylcholine metabolism and the capacity for more adaptive behavior.” From Psyc Abstracts 36:01:1DK72M. (PsycINFO Database Record (c) 2006 APA, all rights reserved)

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