Effect of adrenalectomy on the attenuation of a conditioned avoidance response by ECS in the rat

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Hypothesis: Adrenal glands are essential for ECS to attenuate a conditioned avoidance response. 60 rats were divided into 3 groups of 20 each: bilateral adrenalectomy, sham-operated, control. Each of these was divided into ECS and pseudo-ECS. After surgery each S was trained in a shuttle alley to a criterion of 20 consecutive avoidances. Ss were then given either 21 ECS or pseudo-ECS treatments over 11 days. The dependent variable was the number of avoidances made on a test day 24 hr. after the last ECS of pseudo-ECS treatment. The results showed that ECS significantly attenuated the conditioned avoidance response in intact, sham-operated, and adrenalectomized rats. It was concluded that the adrenals are not necessary for ECS to attenuate an avoidance response. (PsycINFO Database Record (c) 2006 APA, all rights reserved)

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