Effects of autonomic drugs on imprinting

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The adrenergic stimulants, amphetamine, ephedrine, and epinephrine, facilitated following behavior up to 18 hr. of age and interfered with it at later ages. The cholinergic stimulant, neostigmine, had no statistically significant effect, while atropine, a cholinergic blocking agent and central stimulant, facilitated at 8 hr. and interfered at all later ages tested. Hexamethonium, which antagonizes the nicotinic action of acetylcholine at the autonomic ganglia, facilitated at 8 and 24 hr. and had no interfering effects. Similar effects were observed under the influence of ergotamine, a vasoconstrictor and adrenergic blocking agent, and ergonovine, an ergot alkaloid with no known autonomic or vasomotor action. These drugs affect both the initial imprinting performance and the acquisition of the following behavior. (PsycINFO Database Record (c) 2006 APA, all rights reserved)

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