Evaluation of the osmotic effects of glucose loads in food satiation

    loading  Checking for direct PDF access through Ovid


Osmotic theories of food intake predict that ingestion of hypertonic glucose and NaCl should concomitantly produce food satiety and thirst. 24 rats were tested, after ad-lib. feeding and 22-hr. food deprived. 2-hr. food and water intake tests followed stomach loads of sham tubing, or 3% body weight of water, 1 M glucose, or .5 M NaCl. Hunger increased all intakes without interacting with loads. Water, a known hydrator, decreased water intake without changing food intake. NaCl, a known dehydrator, decreased food and increased water intake. Glucose decreased food intake but also decreased water intake. NaCl satiety may be osmotic, but glucose, acting like a hydrator rather than a dehydrator, satiates via a metabolic rather than a colligative route. (PsycINFO Database Record (c) 2006 APA, all rights reserved)

    loading  Loading Related Articles