Postirradiation saccharin avoidance in rats as a function of the interval between ingestion and exposure

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4 groups of 10 rats were subjected to delay periods of 3, 60, 120, and 180 min. between cessation of saccharin ingestion and onset of x-irradiation. 4 similar groups were shamirradiated and 4 had no fluid prior to irradiation. Observations for 24 posttreatment days with a choice of water and saccharin revealed no significant differences among experimental groups. The irradiated control groups evidenced significant avoidance behavior for 4 days. It was concluded that saccharin avoidance conditioning does not fall within the classical conditioning paradigm and other factors are needed to account for the avoidance behavior of the irradiated controls. (PsycINFO Database Record (c) 2006 APA, all rights reserved)

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