Effects of scopolamine on exploratory motivated behavior

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7 scopolamine injected rats, motivated by the opportunity for exploration, made significantly more exploratory choices than 14 controls in a T maze. They reversed this position habit and again showed superior choice performance. They ran significantly slower than controls early in training, but failed to show the speed and activity decrements characteristic of the controls. The data indicate that central acetylcholine activity impairs an animal's ability to habituate to novelty. (PsycINFO Database Record (c) 2006 APA, all rights reserved)

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