Influence of osmotic and caloric loads upon lateral hypothalamic self-stimulation

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5 rats were implanted with lateral hypothalamic electrodes which elicited feeding as well as self-stimulation. Although both hypertonic saline and glucose loads were found to decrease self-stimulation rate, hypertonic saline acted through its osmotic properties whereas hypertonic glucose exerted a metabolic influence upon hypothalamic centers. (PsycINFO Database Record (c) 2006 APA, all rights reserved)

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