Effects of fighting, genotype, and amphetamine sulfate on body temperature of mice


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Abstract

Studied the complex interaction between behavior, genotype, drug effects, and internal physiological reactions. Fighting significantly elevated body temperature in male mice of both the c57bl/6 and balb/c inbred strains, and may have contributed to the increased toxicity of amphetamine sulfate in grouped ss. This drug had widely different effects on the 2 genotypes, lowering temperatures in c57s at all levels tested, but raising it in balbs at 10 mg/kg and above. At 10 mg/kg fighting was inhibited in c57s but not in balbs, except when elevated temperatures reached lethal levels. (23 ref.) (PsycINFO Database Record (c) 2006 APA, all rights reserved)

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