Detection of electrical brain stimulation at hypothalamic and septal sites in rats


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Abstract

Studied the detectability of electrical brain stimulation in 4 male Charles River CD strain rats using a “yes/no” psychophysical procedure. For each S, either septal or hypothalamic stimulation served as the discriminative stimulus, and stimulation at the other site served as the reinforcement for all correct responses. Detection thresholds were determined for 5 different train durations. The psychometric functions obtained were S-shaped and highly reminiscent of those seen in classical psychophysics. Threshold intensity was a monotonically decreasing function of train duration in the range 30–240 msec. Expressed in terms of log charge per stimulus presentation, threshold was a linear function of log stimulus duration in this range. Results demonstrate partial temporal summation. (19 ref) (PsycINFO Database Record (c) 2006 APA, all rights reserved)

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