Telemetered heart rates of immunosympathectomized and/or adrenal-medullectomized mice during behavioral tasks

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Studied the effects of immunosympathectomy and/or adrenal medullectomy in Swiss-Webster mice in the open field and in each S's home environment. Heart rates (HRs) were monitored via telemetry. Mobility and defecation in the open field were not significantly affected by either immunosympathectomy or adrenal medullectomy. Adrenal medullectomy did affect the relationships between HR and mobility or defecation. The negative correlation between HR and activity of 23 adrenal-intact (AI) Ss became insignificantly positive for 17 adrenal-medullectomized (AM) Ss. Defecating control AI Ss had high HRs, and defecating immunosympathectomized (IS) AM Ss had low HRs. The IS Ss were able to achieve HRs as high as those of controls (>800 bpm) when stressed, but these HRs became significantly lower than those of controls in a short time. (23 ref) (PsycINFO Database Record (c) 2006 APA, all rights reserved)

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