Comparison of efficacy of methyl prednisolone and triamcinolone in wrist ganglion using double dart technique and its application in an Indian population

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Ganglion cysts are benign soft-tissue tumors most commonly encountered in the wrist. Treatment modalities described for ganglion cysts include conservative therapy, aspiration, steroid injection, and surgical excision. The purpose of the study was to compare the efficacy of methyl prednisolone and triamcinolone in wrist ganglia using the double dart technique in an Indian population.


All wrist ganglia (dorsal and volar) were included in the study. Patients with diabetes mellitus, tuberculosis, or rheumatoid arthritis were not included in the study. The patients included in the study were randomly divided in two groups: in one group (n=24), aspiration and methyl prednisolone acetate, 1 mL (40 mg) was injected, and in the other group (n=24) aspiration and triamcinolone acetonide, 1 mL (40 mg) was injected using the double dart technique.


Of the 48 patients included in the study, 36 (75%) were women and 12 (25%) were men, showing a female preponderance. The mean age of the patients was 37.18±6.38 yr. There was no significant difference between the methyl prednisolone group and the triamcinolone group in terms of recurrence (Fisher’s exact test, P=1.6). There were no complications in either group, but the triamcinolone group reported more pain at the injection site.


Injection with methyl prednisolone is as effective as injection with triamcinolone and avoids post-injection pain.

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