Persistent Chlorpromazine Deposits in Donor Corneal Tissue After Corneal Transplantation

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PurposeTo present unusual cases with corneal graft deposits and discuss eye bank criteria concerning donors treated with phenothiazines.MethodsWe examined two patients with unusual corneal graft deposits after uneventful corneal transplantation. Donors“ files and eye bank procedures were reviewed.ResultsFine corneal endothelial punctate deposits were detected in both corneal grafts and did not resolve in the following 18 months.ConclusionTo our knowledge, this is the first case report documenting transplantation of corneas with chlorpromazine deposits. Delicate corneal findings can be missed before transplantation.

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