Recurrent Corneal Hypertrophic Scar After Laser-Assisted Subepithelial Keratectomy With Mitomycin C Treatment

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Purpose:To report recurrent corneal hypertrophic scar after laser-assisted subepithelial keratectomy (LASEK) with mitomycin C treatment.Methods:Two patients experienced decreased visual acuity in 1 eye arising from elevated corneal opacity about 12 months after uneventful LASEK with intraoperative mitomycin C application. The elevated opacities were easily removed mechanically.Results:Pathologic examinations showed irregular arrangement of collagen fibers and myofibroblasts, diagnosed as hypertrophic scars. The lesions recurred at about 4-month intervals, despite repeated debridement with and without prophylactic mitomycin C treatment.Conclusions:Recurrent corneal hypertrophic scar may be a rare complication after LASEK treatment with mitomycin C application.

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