Mitomycin-C for Mucous Membrane Overgrowth in OOKP Eyes

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Purpose:The aim of this study was to report the use of mitomycin-C (MMC) in the treatment of mucous membrane overgrowth in eyes with osteo-odonto-keratoprosthesis (OOKP).Methods:Records of 4 cases with mucous membrane overgrowth after stage 2 OOKP surgery were reviewed.Results:All the patients had undergone a mucous membrane trimming procedure followed by MMC application. None of the patients had any episode of recurrence of the mucous membrane overgrowth after a single application of MMC in the follow-up period that ranged from 1 to 11 years.Conclusions:MMC can successfully arrest mucous membrane overgrowth in OOKP-implanted eyes including refractory cases.

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