Avulsion of a calcaneal tuberosity can be the initial presentation of a neuropathic fracture. Neuropathic fracture should be investigated in patients who appear without a history of significant indirect or direct trauma. Neuropathic fractures should always be considered in patients with diabetes mellitus. The diagnosis of neuropathic calcaneal tuberosity avulsion fracture alters the prognosis and treatment of this injury. Two cases of bilateral fracture avulsions are reported to emphasize problems in diagnosis and treatment.