Hazards ratios for venous thromboembolism in heterozygotes and homozygotes for factor V Leiden in a random sample of the adult Danish population as compared to noncarriers for the mutation are increased but lower than those observed in other case-control studies.Source:
Juul K et al. Factor V Leiden and the risk of thromboembolism in the adult Danish population. Ann Intern Med. 2004:140:330-337.