In a randomized, placebo-controlled, double-blind trial, the administration of low-dose corticosteroids to patients with respiratory failure who had relative adrenal insufficiency resulted in shorter weaning periods and high rates of liberation from mechanical ventilation.Source:
Huang CJ, Lin HC. Association between adrenal insufficiency and ventilator weaning. Am J Respir Crit Care Med. 2006;173:276-280.