Unexpected Functional Consequences of the Loss of the Autophagy-Related Conjugation System

    loading  Checking for direct PDF access through Ovid

Abstract

We discuss the recent finding by Mizishima’s group regarding the role of the autophagy-related conjugation system in mediating the closure of autophagosomes and its implication in the study of autophagy in mammalian cells. The study not only shows a novel function of the autophagy-related conjugation system but also indicates that mammalian cells are capable of generating autophagosomes even without it.

Related Topics

    loading  Loading Related Articles