Intestinal parasites infections caused by a variety of worms are very common in low-income people without access to sewage and treated water. Contamination occurs in various forms and the main one is the intake of contaminated food or water and through the skin by small wounds. The host response will be different according to the place of parasite replication: intra or extracellular. Usually the musculoskeletal symptom develops within a period of a few days after the intestinal infection. And the clinical manifestations are more likely similar to those seems in Spondiloarthropathies. It is more frequent in children and adolescent, and a slight prevalence for female. Many parasites are able to bypass the host's immune system, and parasitic disease is the prototype of chronic infection in humans. Persistent parasites have the capacity to release large quantities of antigens, inducing a variety of immunologic reactions.