DOI: 10.1097/DAD.0000000000000102
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PMID: 25607324
Issn Print: 0193-1091
Publication Date: 2015/02/01
Solitary, Well-Circumscribed Depressed Palmar Lesion: Challenge
Ferdinand Toberer; Siegfried Werchau; Markus Hantschke; Jessica Hassel; Alexander Enk; Eva Hadaschik
+ Author Information
Author Information: Department of Dermatology, Ruprecht-Karls-University of Heidelberg, Heidelberg, Germany;
Excerpt
A 72-year-old white woman, otherwise healthy, presented with a 5-year history of a solitary, sharply marginated flat-based patch of depressed skin on her left thenar eminence (Fig. 1). The lesion was neither painful nor pruritic, and the patient denied any history of trauma. The remaining integument and the oral mucosa revealed no abnormal findings. A punch biopsy was performed and the histopathologic examination showed thick stratum corneum at the periphery and an abrupt step-down in the cornified layer centrally. The zone of hypokeratosis included compact orthokeratin atop thin zones of parakeratosis. Neither cornoid lamellae nor fungal hyphae were present (Fig. 2).
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