Twelve cases of primary angiomyolipoma of the liver are presented. Histologically the tumors were similar to renal angiomyolipomas, containing tortuous blood vessels, smooth muscle, and fat. Some also contained prominent hematopoietic elements (angiomyo-myelo-lipomas). The tumors may have necrosis and pleomorphic epithelioid smooth muscle cells which have led some to be mistaken for malignancies. Despite the similarity to their renal analogs, hepatic angiomyolipomas are not associated with tuberous sclerosis.