Clear cell change in primary thyroid tumors: A study of 38 cases

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ABSTRACT<Thirty-eight primary thyroid neoplasms with extensive (3=%) clear cell changes were studied. These were divided into four categories: 1) Hurthle cell tumors, 10 cases; 2) follicular tumors, 17 cases (two of them having a signetring or lipoblast-like appearance); 3) papillary carcinomas, seven cases; and 4) undifferentiated carcinomas, four cases. These were compared with eight cases of renal cell carcinoma metastatic to the thyroid.

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