Coagulopathy After Reinfusion of Autologous Scavenged Red Blood Cells

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Abstract

Cell scavenging techniques reduce homologous blood transfusion (1–5). Coagulopathy, one of the potential hazards of reinfusing scavenged autologous blood, is an infrequent occurrence when automated cell processing systems are used to collect, anticoagulate, and wash scavenged red blood cells (1–5). Bleeding problems associated with autologous red blood cell administration are believed to be primarily a result of dilutional rather than disseminated coagulopathy (6–9). When disseminated intravascular coagulopathy is observed during the reinfusion of scavenged autologous blood, concomitant problems such as shock and tissue trauma, rather than the autologous red blood cells per se, are the usual causes of the coagulopathy (6,7). We describe two patients who experienced disseminated coagulopathy after reinfusion of autologous scavenged red blood cells collected during elective surgery for scoliosis correction.

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