Xenon Inhibits but N2o Enhances Ketamine-induced c-fos Expression in the Rat Posterior Cingulate and Retrosplenial Cortices

Atsushi Nagata, Shin-ichi Nakao, Nobuyasu Nishizawa, Munehiro Masuzawa, Takefumi Inada, Kohei Murao, Etsuko Miyamoto, Koh Shingu

doi:10.1213/00000539-200102000-00016

DOI: 10.1213/00000539-200102000-00016

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PMID: 11159233

Issn Print: 0003-2999

Publication Date: 2001/02/01

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Atsushi Nagata; Shin-ichi Nakao; Nobuyasu Nishizawa; Munehiro Masuzawa; Takefumi Inada; Kohei Murao; Etsuko Miyamoto; Koh Shingu


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Abstract

Implications

Xenon may suppress adverse neuronal effects of ketamine. Conversely, combined use of N2O and ketamine may increase the risk of neuronal adverse effects, such as psychotomimetic effects.


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Xenon Inhibits but N2O Enhances Ketamine-Induced c-Fos Expression in the Rat Posterior Cingulate and Retrosplenial Cortices

Abstract

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