Positive Pressure Ventilation with the ProSeal Versus Classic Laryngeal Mask Airway: A Randomized, Crossover Study of Healthy Female Patients

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The ProSeal™ laryngeal mask airway (PLMA) (Laryngeal Mask Company, Henley-on-Thames, UK) is a new laryngeal mask device with a modified cuff and a drainage tube (1). Preliminary trials have shown that the PLMA forms a more effective seal than the standard laryngeal mask airway (LMA) during a static oropharyngeal leak test and isolates the respiratory tract from the gastrointestinal tract when correctly positioned (1,2), but there is no evidence that it is a better ventilatory device. In the following randomized, cross-over trial, we tested the hypothesis that the PLMA is a more effective ventilatory device than the LMA in healthy anesthetized females at 8 and 12 mL/kg tidal volume with the cuff semi- or fully inflated.
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