A Predictive Model for Lymph Node Yield in Colon Cancer Resection Specimens

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Excerpt

In the current TNM Classification of Malignant Tumors staging system for colon cancer, the presence of metastatic colon cancer in the regional mesenteric lymph nodes is the primary determinant for the use of adjuvant chemotherapy.1 Several retrospective single institution studies have demonstrated an association between increased numbers of examined lymph nodes and the presence of lymph node (LN) metastasis.2,3 Furthermore, an analysis of the National Cancer Database found that patient outcomes after treatment for T3N0 colon cancer can be stratified by the quantity of LNs retrieved.

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