Beneficial effects of statins on perioperative cardiovascular outcome

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Purpose of review

This review evaluates clinical and experimental articles that have recently been published on the cardioprotective effect of perioperative statin therapy.

Recent findings

Perioperative statin therapy improves short and long-term cardiac outcome following noncardiac surgery. This cardiovascular protection has been attributed to the so-called pleiotropic effects, which have a positive effect on plaque stability. With no clinical studies reporting an increased incidence of adverse effects of perioperative statin use, it appears to be a safe and helpful therapeutic option.


Perioperative statin therapy may stabilize coronary plaques due to pleiotropic effects and results in a reduction of perioperative cardiovascular complications.

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