Abstract
The well-differentiated thyroid carcinomas include papillary and follicular thyroid cancers. Approximately 14,000 new cases of thyroid carcinoma are diagnosed in the United States annually, but there are only 1100 deaths annually from thyroid malignancies. This relatively good prognosis is attributed to the biology of thyroid carcinoma and the current methods of treatment. Current investigations are aimed at expanding our understanding of thyroid carcinoma biology and optimizing treatment in a cost-effective manner.