Issn Print: 0894-9115
Publication Date: 1996/03/01
CEREBRAL AUTOREGULATION IN PHYSICAL MEDICINE
Excerpt
The purpose of this study was to investigate the effects of changes of core temperature on cerebral autoregulation. Cerebral autoregulation was measured 100 times in 15 volunteers (V). One group of eight V (mean age: 27 years; sex: 3f/5m) received cold-baths for 20 minutes at 22°C. Each V was administered nine autoregulation tests (AT), two before, five during, and two after the bath. Another group of seven V (mean age: 52 years; sex: 4f/3m) received hyperthermic baths at a water temperature of 36-42°C, increasing 1°C every 5 min. In this group, each V was administered four AT, one before, two during, and one after the bath. Dynamic autoregulation was measured by the response of cerebral blood flow velocity to a transient decrease of the mean arterial blood pressure, induced by rapid deflation of thigh cuffs. The autoregulation index (ARI) was used to quantify the response. Further parameters were core temperature (CT) [°C], blood pressure [mmHg] and CO2et [mmHg]. During hypothermic baths, core temperature decreased by 0.3°C (P < 0.001) as measured between preliminary the phase and the end of bath, ARI decreased significantly (P < 0.05) from 5.3 (CT 36.7°) before the bath to 4.3 (CT 36.5°) during the bath. During hyperthermic baths, ARI increased from 6 to 8.8 (P < 0.05), with an increase of core temperature of 0.6°C. Dynamic Cerebral Autoregulation is dependent on core temperature. High CT increased ARI and low CT decreased ARI.
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