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Winslow C, Rozovsky J: Effect of spinal cord injury on the respiratory system. Am J Phys Med Rehabil 2003;82:803–814.There are >200,000 persons living with a spinal cord injury in the United States, with approximately 10,000 new cases of traumatic injury per year. Advances in the care of these patients have significantly reduced acute and long-term mortality rates, although life expectancy remains decreased. This article will review the alterations in respiratory mechanics resulting from a spinal cord injury and will examine the contribution of respiratory complications to morbidity and mortality associated with various types of spinal cord injury.