ln-111 Granulocyte Response to Intervening Surgery Evidence of Sustained in Vivo Viability

Abstract

A patient with chronic osteomyelitis had surgery performed between the early and delayed images of an ln-111 granulocyte scan. The early images showed no uptake, while the delayed images demonstrated marked soft tissue uptake, which was felt to be secondary to the inflammation of the intervening surgery. It was concluded that granulocytes, when labeled with ln-111, remain viable and can respond to inflammation that occurs after their injection.