FDG PET Brain Imaging in Neuropsychiatric Systemic Lupus Erythematosis With Choreic Symptoms

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Chorea is a rare manifestation of neuropsychiatric systemic lupus erythematosus, and is probably caused by immune-mediated hypofunction of the contralateral striatum. Conventional imaging with brain computed tomography or magnetic resonance imaging often fails to show any structural lesions. We report a case of systemic lupus erythematosus-associated chorea in which brain F-18 flourodeoxyglucose positron emission tomography imaging showed disturbances in striatal metabolism in the absence of structural damage on magnetic resonance imaging. A follow-up positron emission tomography scan showed normalization of striatal metabolism, which was correlated with clinical remission.

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