Imipramine (Tofranil®) intoxication: a case report and review of management

Abstract

A fatal case of imipramine intoxication is reported. The patient presented with the typical findings of imipramine poisoning: coma, fixed dilated pupils, cardiac disturbances, and hyperpyrexia which, at first, were attributed to head trauma. The importance of prompt recognition of such poisoning is emphasized, and a general scheme of treatment is outlined.