Issn Print: 0090-3493
Publication Date: 2004/12/01
HSP72 PROTECTS MITOCHONDRIA AND MICROTUBULES IN IEC18 CELLS: 10
Jennifer L Liedel; Eugene Chang
Excerpt
Apoptosis and necrosis are the final manifestations of intestinal epithelial injury. The protective role of heat shock proteins(HSPs) in the cellular response to stress is well-known. Specific mechanisms by which HSPs prevent apoptosis are poorly characterized, but involve mitochondria as initiators of the apoptotic cascade.