Primary low-grade B cell non-hodgkin's lymphoma of MALT type simultaneously arising in the colon and in the lung: Report of a case

Abstract

Gastrointestinal lymphomas are the most common extranodal non-Hodgkin's lymphomas. Most gastrointestinal lymphomas are low-grade B cell lymphomas and originate from the mucosa-associated lymphoid tissue (mucosa-associated lymphoid tissue-type lymphoma or extranodal marginal zone B cell lymphoma of mucosa-associated lymphoid tissue type according to the Revised European American Lymphoma classification). Other mucosa-associated lymphoid tissue-type lymphomas arise in the salivary glands, thyroid gland, and in the lung (bronchus-associated lymphoid tissue). Here, we report the first case of a monoclonal mucosa-associated lymphoid tissue lymphoma with simultaneous manifestation in the colonic and bronchial mucosa in a 62-year-old patient. With mitoxantrone, chlorambucil, and prednisone polychemotherapy, a complete year-long remission was achieved.