Issn Print: 0265-0215

Publication Date: 2005/05/01


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Training and education tool for muscle relaxant administration regimes: A-762

T. Mendonça; H. Magalhães; S. Esteves; P. Lago

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Background and Goal of Study: Development of a package to be used as an advanced tool for education and training purposes of drug administration regimes.
Materials and Methods: The package has been developed in MATLAB language, using the current features on graphic user interfaces, and may be used as an advanced simulation tool for the test and comparison of fairly different trial situations, under a variety of circumstances and muscle relaxant drugs, namely atracurium, cisatracurium, rocuronium and vecuronium. The software incorporates randomly generation of pharmacokinetic/pharmacodynamic models driven by simulated drugs administration regimes (bolus and/or continuous infusion). The package also incorporates several control strategies1 and it can be also used for the automatic control on patients undergoing surgery2. In order to provide a wide broad of situations, the friendly user interface and the toolbar enables/disables a variety of different options namely those related with operating mode, reference level, control strategies and the filtering methods.
Results and Discussions: The figure illustrates a graphical environment of a simulated case under manual control strategy.
Conclusion(s): The special features of this package give to the clinical staff a powerful tool, providing a variety of test situations namely a good insight on drug models and control strategies.
Acknowledgement: Portuguese Foundation for Science and Technology.
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