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Materials and Methods: 84 patients (age 51.32 ± 8.73, F:M = 38:46) suffering aneurismal subarachnoid bleeding were assessed for their neurological status and blood oxygenation at the moment of their admission (day 3.28 ± 2.56). Their most common other diseases were hypertension (n = 67, 79.7%) and COPD (n = 17, 20.231%). Hunt and Hess, Fisher, GCS and GOS (14-th day) scales as well as seizure events and massive vomits were assessed. Blood oxygenation was valued through PaO2. Data are given as mean ± SD, T-test is used for statistical evaluation and p < 0.05 is considered as statistically significant.
Results and Discussion: Decrease of PaO2 at admission is strongly influenced not only by values of Hunt and Hess or Fisher Scales. In our patients with GCS 12-15 pts, who suffered seizures (PaO2 = 65.88 ± 10.54, n = 18) or massive vomits (PaO2 = 71.44 ± 11.92, n = 21), although they did not show significant difference on Hunt and Hess or Fisher scales with others (PaO2 = 87.03 ± 7.15, n = 30) the difference observed is significant (p < 0.01). Patients with GCS less than 12 pts (PaO2 = 71.86 ± 14.22, n = 15) had significantly decreased PaO2 (p < 0.001). We consider important the observation, that patients have showed PaO2 > 80 mmHg (n = 49), had significantly lower score on Hunt and Hess scale (2.12 ± 1.11 to 1.53 ± 0.74, p < 0.01) and significantly higher upon GOS (3.62 ± 1.52 to 2.86 ± 1.61, p < 0.05). PaO2 in patients with COPD showed no statistical significance compared with other patients at admission (p = 0.19).
Conclusions: These results suggest that during the early period after the outbreak of aneurismal subarachnoid bleeding, seizures, massive vomits or presence of GCS less than 12 pts exert a strong influence on decreasing the blood oxygenation. Our patients with PaO2 over 80 mmHg at admission had a significantly better neurological status and better outcome.
